The drug "Trimystin"( ointment): instructions for use, description, composition and reviews

How to apply "Trimistin" ointment? Instructions for use, reviews about the product for external use will be presented later. Also you will learn about what substances are part of the drug, how much it costs, whether it has analogues, and what contraindications should be known to patients.

Composition and packaging

The preparation "Trimystin"( ointment), the instruction for which is contained in a cardboard package, includes such active ingredients as miramistin and triamcinolone acetonide. As for the auxiliary components, they include: purified water, stearyl and cetyl alcohols, propylene glycol and beta-cyclodextrin.

For sale a translucent gel of white color and gel-like consistency with a pronounced specific aroma comes in aluminum tubes.

Farmakodinamika

What is a medicine "Trimistin"( ointment)?Instruction for use informs that this combination is intended for outdoor use only.

Triamcinolone, which is part of the ointment, has a pronounced anti-allergic, anti-exudative and anti-inflammatory properties.

By associating with specific protein receptors, the said substance is capable of correcting the expression of corticoidependent genes, as well as influencing the synthesis of the protein itself.

Triamcinolone reduces the activity, release and production of inflammatory mediators( histamine, lysosomal enzymes, prostaglandin and kinin).It also reduces vasodilation and vascular permeability at the site of inflammation and depresses the migration of cells to the outbreak.

This drug is involved in the stabilization of lysosomal enzymes of leukocyte membranes, prevents recognition of antigens and suppresses the replication of antibodies. It also inhibits the release of interleukins and gamma-interferon from lymphocytes and macrophages.

What other properties are inherent in the medicine "Trimistin"?Instructions for use inform that this gel inhibits the release of inflammatory mediators by eosinophils, promotes the formation of lipocortin and stabilizes the membranes of mast cells.

In the presence of injured tissues, all of these effects are directly involved in the suppression of inflammatory reactions that occur during mechanical, chemical and immune damage.

With regard to such an antiseptic component as Miramistin, it has an extensive spectrum of action. This substance has a bactericidal effect( hydrophobically affects the membranes of bacteria).

Features of the preparation

How does the "Trimistin" gel work? Instructions for use( analogues of the ointments are indicated below) informs that the effect of this drug extends mainly to gram-positive microorganisms, as well as to certain gram-negative bacteria, including aerobes and anaerobes.

In addition, the preparation under consideration has a detrimental effect on the spore-forming and spore-forming microflora in the form of monocultures and microbial associations( including hospital strains that are resistant to antibiotic therapy).

The antifungal activity of an active substance such as myramistin encompasses yeast-like and yeast fungi, ascomycetes and dermatophytes. This substance prevents the infection of wounds by activating regeneration processes.

Pharmacokinetics

The chemical and physical properties of the preparation, as well as its high molecular weight sorption polymers, retain the active ingredients at the site of application and prevent their entry into the systemic bloodstream.

Indications

When should I use the "Trimistin" gel? The instruction, the description of the drug report that this medication is prescribed in the presence of skin diseases of inflammatory origin, including those aggravated by bacterial or fungal infection:

• eczema, parapsoriasis, lupus erythematosus;
• atopic dermatitis, Duhring's dermatitis, pemphigus;
• neurodermatitis, seborrheic dermatitis, cutaneous lymphoma;
• psoriasis, photodermatosis, contact dermatitis.

Contraindications

What diseases prohibit the use of the drug "Trimistin"( ointment)?Instruction for use indicates some contraindications to the external remedy. These include:

• pregnancy period;
• is a tuberculosis of the skin that is concentrated in the place of application of the ointment;
• skin lesions of a syphilitic nature;
• age under 1 year;
• hypersensitivity to constituent ingredients;
• skin reactions that occurred after vaccination;
• skin cancer.

Preparation "Trimistin"( ointment): instruction for use

The drug should only be used externally. Ointment should be applied to the damaged areas of the skin in a thin layer, slightly rubbing with pads of fingers.

This procedure should be performed twice a day for 7-10 days. After the termination of therapy the inflammatory process should stop completely, a skin - to be cleared, and an itch - to stop.

When the exudate appears at the site of application, the skin area should first be treated with 1% solution of boric acid, 3% hydrogen peroxide or 0.05% chlorhexidine bigluconate, and only then use the medication.

It is also allowed to apply the ointment using a sterile dressing.

Side effects of

This medication rarely causes side effects. Although in some cases, when applying ointment, patients can still have a slight burning sensation.

Drug overdose

When applying ointment to large areas of the affected skin, a small amount of the drug can enter the systemic bloodstream. This phenomenon does not lead to toxic effects.

Drug Interaction

The effectiveness of the "Trimistin" ointment increases significantly with the simultaneous use of antibiotics, antimicrobials and systemic antihistamines. It should also be noted that the effectiveness of the gel under consideration is markedly reduced when it is combined with other external preparations, which include sorbents.

Special recommendations

The effectiveness of the ointment may be slightly weakened when applied to the skin areas, where a large number of purulent-necrotic secretions are contained. Therefore, before using this product, the veil should be thoroughly treated with a soap solution or antiseptic.

Cost and analogues

The price of the drug in question varies between 130-180 rubles. As for the analogs, this means they do not. If the ointment "Trimistin" does not suit you, then to replace it with similar medications you should consult a doctor.

Reviews about the external tool

Now you know what the "Trimistin"( ointment) medication is. The price, the instruction, analogues, responses and indications of this preparation are described in this article.

According to the patients' feedback, the above-mentioned drug copes with the task perfectly. It is very popular with people who have various skin diseases. In this case, it should be remembered that the drug in question is not recommended for a long time, and also exceed the dosages recommended by the dermatologist.