"Supirocin"( ointment): instruction manual, reviews
Today various kinds of ointments and creams are used to treat various skin diseases. Each of these drugs has several advantages and disadvantages. Some medicines are combined, and their action is due to the active components that make up their composition."Supirocin" - ointment, which is used exclusively externally, it allows you to get rid of boils, eczema and some dermatitis.
"Supirocin" is an ointment containing a component such as mupirocin. This substance is an antibiotic that produces microorganisms Pseudomonas fluorescens. Mupirocin is able to suppress the synthesis of protein bacteria. The substance achieves a similar effect by reversible binding with isoleucyl-transport RNA synthetase. This prevents the penetration of the harmful component into the protein chains that have just begun to be built.
In small concentrations, this antibiotic is able to have bacteriostatic action, in large quantities - bactericidal. But this is not all the properties of the component that contains "Supirocin"( ointment).
Due to its unique structure and specific mechanism of action, the substance shows no signs of cross-resistance in combination with other antibiotics. Also, there is little risk of the emergence of resistant strains of bacteria, if, of course, correctly apply the drug.
Glucocorticosteroid in ointment
Another active ingredient that contains the drug is betamethasone. This substance is a glucocorticosteroid. Thanks to this substance, "Supirocin"( ointment) has antiproliferative, anti-edematous, anti-allergic and local anti-inflammatory effect. In addition, the drug has a vasoconstrictive effect, in contrast to other creams, which also contain glucocorticosteroids. Due to the limited absorption of the ointment through the skin, systemic effects are negligible.
When this drug is prescribed
Often an ointment is prescribed to cure some skin infections. The drug perfectly fights with:
- Atopic dermatitis.
- Diffuse neurodermitis.
- Contact dermatitis.
- Exfoliative dermatitis.
- Herpetiform dermatitis.
- Seborrheic dermatitis.
- Complicated bacterial secondary infections.
Features of the preparation
"Supirocin" - ointment, which is often used for the treatment of skin ailments. The antibiotic included in the product is not able to penetrate deep layers of unaffected skin. If adsorption occurs through the damaged site, the substance is metabolized and converted into an inactive component - monic acid, which, in turn, is rapidly excreted from the body through the kidneys.
Betamethasone dipropionate is a lipophilic substance that easily penetrates the deep layers of the skin through the stratum corneum. The component is not biotransformed. When applied to the skin in the area of the clutches, absorption increases. Also, a similar phenomenon is noted if you use "Supirocin" ointment, reviews of which are practically positive, on the affected parts of the epidermis, where the onset of the inflammatory process begins. Absorption increases with frequent application of the drug on a significant surface of the skin. It should be noted that in children the absorption of betamethasone dipropionate proceeds several times faster than in adults.
"Supirocin B": instruction
As the testimonials show, it is necessary to apply an ointment to the affected areas of the skin with a very thin layer. It is necessary to conduct such a procedure up to 3 times a day. The course of therapy can last from 5 to 14 days. In many respects it depends on what kind of skin infections bother the patient.
Specialists recommend the use of the composition solely for the treatment of all affected skin areas, the area of which is not more than 100 square centimeters. If, for 3 to 5 days, the patient does not have any clinical effect, then a second examination is necessary.
Side Effects of
In some cases, "Supirocin"( ointment), the price of which on average ranges from 220 to 450 rubles, can cause side effects, among them:
- Skin atrophy.
- Secondary infection.
- Maceration of the skin.
- Contact allergic dermatitis.
- Periorum dermatitis.
- Acne vulgaris.
- Dryness of the skin.
- Itching and burning.
Features of the drug
As the reviews show, if the instructions for use are not observed, an overdose may occur. It is manifested by the reversible oppression of the hypothalamic-pituitary-adrenal system. There are cases of Cushing's syndrome, glycosuria and hyperglycemia.
In some cases it is not possible to use "Supirocin"( ointment).Experts say that this drug is prohibited during lactation, as well as during pregnancy. The interaction of this drug with other medications was not revealed.
When you can not use the drug
There are times when you can not use "Supirocin"( ointment).Experts' reviews show that this drug should not be used with:
- Skin manifestations of syphilis.
- Tuberculosis of the skin.
- Fungal, viral and bacterial skin diseases.
- Trophic ulcers, the appearance of which is associated with varicose veins.
- Sarcoma, xanthoma, hemangioma, melanoma, athere, nevus, skin cancer.
- Acne vulgaris.
- Post-vaccination reactions.
In addition, it is prohibited to use the drug to treat skin infections in children under 12 years of age. Another contraindication is the individual intolerance of any component that is part of the "Supirocin" ointment.
In some cases, the drug should be taken with caution. Patients who suffer from cataracts, tuberculosis, glaucoma and diabetes mellitus, experts do not recommend the use of ointment on large areas of skin.